Dr. Johanna Bischof
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Curriculum Vitae

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Dr. Johanna Bischof

Allen Discovery Center at Tufts University,
Suite 4600, 200 Boston Avenue
Medford, MA 01255
+1 617 627 4181


johanna.bischof@tufts.edu
@JojoBischof

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 Research interests
  • Formation and maintenance of patterns on the single-cell and organism level during development and regeneration
  • Regeneration of the nervous system
  • Role of the nervous system in regeneration
  • High-resolution live-cell imaging

Research experience
 
Sept 2016 – present   Postdoctoral Researcher
                                       In the lab of Dr Michael Levin at Tufts University and the Allen Discovery Center at Tufts
                                      “Pattern determination and the role of the nervous system in planaria regeneration”
                                      “Encoding and transmission of target morphology in the regenerating planarian”
 
Oct 2012                       PhD thesis
          – Aug 2016            In the lab of Dr Peter Lenart at EMBL Heidelberg
                                       “The molecular mechanism of Surface Contraction Waves in the starfish oocyte”
 
March 2012                 Master thesis II (5 month research project included in MRes course)
          – Aug 2012            In the lab of Prof William Wood at the University of Bath
                                       "The Role of integrins and actin binding proteins in immune cell migration in Drosophila embryos"
 
Oct 2011                       Master thesis I (5 month research project included in MRes course)
         – March 2012          In the lab of Dr Paul De Bank at the University of Bath
                                       "Evaluation of Silk/Gelatin scaffolds from muscle tissue engineering”
 
Feb 2011                       Bachelor thesis at the Centre for Regenerative Therapies, TU Dresden
          – June 2011           In the lab of Prof Schwille
                                       “Development of a biophysical assay for simultaneous detection of three different interaction partners in living
                                        cells based on Fluorescence cross-correlation spectroscopy (FCCS)”
 
Aug 2010                      Work placement at the Healing foundation, University of Manchester
          – Oct 2010             In the lab of Prof Mace
                                        “Macrophage differentiation in wound healing”
 
Education
 
Oct 2012                        Doctor of Natural Sciences (PhD) at EMBL Heidelberg and University of Heidelberg
          – Aug 2016            Grade: 1.0 (Highest grade on a scale from 1.0 (best) to 4.0 (worst)),
                                        magna cum laude
 
Sept 2011                       Master of Research (MRes) in Regenerative Medicine
          – Oct 2012             One-year degree.
                                        Grade:  Degree with distinction (Highest grade)
 
Oct 2008                       Bachelor of Science in Molecular Bioengineering, Dresden University of Technology, Dresden
            – Aug 2011          Three-year degree.
                                        Grade:  1.5 (on a scale from 1.0 (best) to 4.0 (worst))

Publications

  1. Pietak*, Bischof*, LaPalme, Morokuma, Levin; Neural Control of Body-plan Axis in Regenerating Planaria, 2019, PLOS Computational Biology, doi:10.1371/journal.pcbi.1006904 , * authors contributed equally to this work

  2. Durant, Bischof, Fields, Morokuma, LaPalme, Hoi, Levin; Early Role of Bioelectric Signaling in the Establishment of Anterior/Posterior Polarity During Planarian Regeneration, 2019, Biophysical Journal, doi:10.1016/j.bpj.2019.01.029

  3. Klughammer, Bischof, Schnellbächer, Callegari, Lenart, Schwarz; Cytoplasmic flows in starfish oocytes are fully determined by cortical contractions, 2018, PLOS Computational Biology, doi:10.1371/journal.pcbi.1006588

  4. Levin, Pietak, Bischof; Planarian Regeneration as a Model of Anatomical Homeostasis: Recent Progress in Biophysical and Computational Approaches, 2018, Seminars in Cell and Developmental Biology, doi: 10.1016/j.semcdb.2018.04.003

  5. Bischof, Brand, Somogyi, Majer, Thome, Mori, Schwarz, Lenart; A cdk1 gradient guides surface contraction waves, 2017, Nature Communications, doi:10.1038/s41467-017-00979-6

Research Support
 
            NIH R01, In review
            Decoding anatomical information transfer in planaria via tissue transplantation
            Role: Co-Author, Dr. Michael Levin, PI ($ 1,250,000)
 
            The Paul G. Allen Frontiers Group, 2015 – current
            Reading and Writing the Morphogenetic Code
            Michael Levin, PI ($ 10,000,000)
            Role: Postdoctoral Researcher, Participant Only
 
            EMBL International PhD Fellowship, 2012 – 2016
            4-year full scholarship (€ 90,000, plus lab overhead fees)
 
            German Academic Scholarship Foundation, 2011 – 2012
            1-year full academic scholarship for Master’s degree outside of Germany (£ 10,000)
           
            German Academic Scholarship Foundation, 2008 – 2011
            3-year educational support scholarship for outstanding undergraduate students (€ 5,500)
 
Teaching experience
 
2017 - present             Organizer and Instructor of the weekly undergraduate journal club
 
2017 - present             Lecturer and Lab Instructor: Bio52 – Experiments in Cell Biology (14 students), Team taught course, Section: The 
                                    role of bioelectricity in planarian regeneration
 
2016 - present             Evaluator of independent undergraduate research reports and presentations (Bio194)
 
2014                            Lecturer and Lab Instructor: EMBO course ‘Marine animal models in evolution and development’ (8 students),     
                                    Team taught course, Section: Microinjection and confocal microscopy on starfish oocytes
 
2013                            Lecturer and Co-Organizer: Graduate student introductory course (50 students), Team taught course, Sections:  
                                    Basic Laboratory Techniques, Model Systems in Biology
 
2013 - 2015                 Lecturer and Lab Instructor: Graduate student introductory course (10 students), Team taught course, Section:   
                                    Cell Biology and Biophysics
 
2013                             Lecturer and Lab Instructor: EMBO course ‘Current Methods in Cell Biology’ (10 students), Team taught course,
                                     Section: Microinjection, confocal microscopy and automated image analysis to understand meiosis in
                                     starfish oocytes
 
Student Mentoring and Supervision

2018 - present              Co-leader of a Tufts Mentoring circle for PhD students in Biology and Biomedical Engineering
 
2016 - 2019                  Tufts Undergraduate students and graduate research assistants mentored:

            Amrutha Chintalapudi, Sophomore 2016 – Senior 2019; Regeneration of the nervous system
 
            Margot Day, Sophomore 2016 – Senior 2019; Repatterning in double-head regeneration, Senior Honors Thesis
 
            Linda Lee, Sophomore 2016 – Senior 2019; Exploring the cytoskeleton in planaria
 
            Claire Kerns, Junior 2019 – present; Exploring the cytoskeleton in planaria
 
            Alice Gelman, Master Student 2019 – present; Regeneration of the nervous system
 
            Joshua LaPalme, Research Assistant, 2017 – present; Long-term repatterning in planaria
 
            Sophie Loman, Research Assistant, 2018 – present; Regeneration of the nervous system
 
            Kelsie Miller, Senior Research Technician, 2018 – present; Automated systems for maintenance of a planarian colony, Molecular  
            analysis of planaria regeneration
 
            Hans Gonzembach, Research Technician, 2017 – present; Planarian colony maintenance


Invited Seminars
 
2018    Duke University, Biology Department, Durham, Host: Dr. Fred Nijhout
 
2016    European Molecular Biology Laboratory (EMBL), Host: Dr. Peter Lenart
 
Conference presentations

  1. EMBO workshop Molecular and cellular basis of regeneration and tissue repair, 2018, Transplantation of bodyplan information between planaria (Poster)

  2. The International Planaria meeting, 2018, Transplantation of bodyplan information between planaria (Poster)

  3. Nature Regeneration Conference, 2017, Transplantation of bodyplan information between planaria (Talk)

  4. Symposium on Dynamics and Mechanisms of Cytokinesis, 2016, Polar body extrusion and the role of surface contraction waves in starfish oocyte cytokinesis (Talk)

  5. Biophysical Society 60th Annual Meeting, 2016, Surface Contraction Waves in the starfish oocyte (Talk)

  6. Physics of Cells and Tissues Conference, 2015, Surface Contraction Waves in the starfish oocyte (Talk)

  7. Gordon Conference on Motile and Contractile Systems, 2015, Surface Contraction Waves in the starfish oocyte (Poster)

  8. Biophysical Society 58th Annual Meeting, 2014, Surface Contraction Waves in the starfish oocyte (Poster)

  9. EMBO Meiosis meeting, 2014, Surface Contraction Waves in the starfish oocyte (Poster)

  10. Jaque Monod Conference on Cell Cycle: Bridging the scales, 2014, Surface Contraction Waves in the starfish oocyte (Poster)

  11. EMBO workshop Oocyte maturation and Fertilization, 2013, Surface Contraction Waves in the starfish oocyte (Poster)
 
Academic Service
 
2019                           Poster Judge at the 2019 Scientista Symposium ‘Science without Borders’
 
2018 – present            Mentor in the Postdoctoral Association Mentoring Circle Program
 
2017 – 2018                Poster Judge at the ASBMB Northeast Regional Meeting
 
2013                            Member of the Core Organizing Team for the 15th EMBL PhD Symposium ‘Competition in Biology’ (Nov 2013)

2011 - 2012                 Student representative for students in graduate taught courses at the department and school level
 
Science communication, outreach and writing
 
2019                            Presenter at Pint of Science Night at the Cambridge Science Festival - Voted Best talk
 
2017                            Bunker Hill Community College – Career panel for STEM students
 
2017 - present            Judge at the local and regional Science and Engineering Fair
 
2017                            Presenter at the AAAS Science Days: Science in the classroom
 
2014 – 2016                Member of the ‘EMBL agents for outreach’, including presentations at Science Movie night, Friends of EMBL    
                                    events, ‘Meet a PhD student’ lunch 
 
2014                            Two-time presenter at the Heidelberg Science Slam
 
2011 – 2015                  Regular contributor for the Life Science section of the online newspaper ‘Experimentation’ 
 
Prizes and Awards

2019                            Best short talk at the Pint of Science Night at the Cambridge Science Festival

2015                            Best short talk at Physics of Cells and Tissues Conference
 
2015                            Best poster at the Gordon Conference “Motile and Contractile Systems”
 

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